+RF Technology

Neuromodulation is a technology that uses electrical stimulation on nerves to modulate nerve activity and alleviate pain.




In the mid-1970s, conventional continuous radiofrequency (CRF) was first used in pain treatment, using high frequency with a temperature of 80° C to the target tissue and resulting in irreversible tissue necrosis to stop the pain single pathway. It was used to treat lumbar radicular pain, intercostal neuralgia, and cervicogenic headaches. However, a high risk of motor deficits and deafferentation syndrome also come with CRF surgery.

Till the early 1990s, Pulse radiofrequency (PRF) was developed. Using short, high-voltage bursts, keeping the heating temperature at 42° C on the target tissue. The mechanism is still unclear, but it significantly lowers the risk of CRF and it has been wildly proved the clinical effect on pain management, including cervical or lumbar facet joint pain, low back pain, chronic cervical radicular pain, idiopathic trigeminal neuralgia, occipital neuralgia, inguinal pain and orchialgia, sacroiliac joint pain, glenohumeral osteoarthritis, and adhesive capsulitis.







In 2008, the founders of GIMER combined PRF to make the +RF technology, itʼs an ultra-high frequency of 500 kHz that has a high penetration rate, no heat sensation during the treatment, no protein denature and no action potential changes. This tech innovation provides a safer, paresthesia-free and prolonged treatment effect for chronic pain patients.

Nowadays, neuromodulation treatment can be used in various clinical situations, such as spinal cord stimulation (SCS) for intractable low back pain, deep brain stimulation (DBS) for Parkinsonʼs disease, vagus nerve stimulation (VNS) for seizures and depression, and sacral nerve stimulation (SNS) for overactive bladder disorder, etc. Our initial focus is on ultra high frequency spinal cord stimulation device addressing chronic pain. In the pipeline we will take this innovative treatment further and apply to other indications, hoping to make positive impacts on the quality of lives of those who suffer from different medical conditions.

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